Version 5.4
Homo sapiens Protein: ATP6V1G3
Summary
InnateDB Protein IDBP-105608.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATP6V1G3
Protein Name ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000309574
InnateDB Gene IDBG-105600 (ATP6V1G3)
Protein Structure
UniProt Annotation
Function Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Subcellular Localization
Disease Associations
Tissue Specificity Kidney. {ECO:0000269PubMed:12384298}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0051117 ATPase binding
Biological Process
GO:0006879 cellular iron ion homeostasis
GO:0008286 insulin receptor signaling pathway
GO:0033572 transferrin transport
GO:0051701 interaction with host
GO:0055085 transmembrane transport
GO:0090382 phagosome maturation
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016471 vacuolar proton-transporting V-type ATPase complex
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96LB4
PhosphoSite PhosphoSite-Q96LB4
TrEMBL
UniProt Splice Variant
Entrez Gene 127124
UniGene Hs.127743
RefSeq NP_579872
HUGO HGNC:18265
OMIM
CCDS CCDS1396
HPRD 16526
IMGT
EMBL AL157402 AY039760 BC101129 BC101130 BC101131
GenPept AAI01130 AAI01131 AAI01132 AAK83465 CAI15638

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca