Homo sapiens Protein: SEMA6D | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||||
InnateDB Protein | IDBP-10569.6 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | SEMA6D | ||||||||||
Protein Name | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D | ||||||||||
Synonyms | |||||||||||
Species | Homo sapiens | ||||||||||
Ensembl Protein | ENSP00000324857 | ||||||||||
InnateDB Gene | IDBG-10567 (SEMA6D) | ||||||||||
Protein Structure | |||||||||||
UniProt Annotation | |||||||||||
Function | Shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons. May also be involved in the maintenance and remodeling of neuronal connections. | ||||||||||
Subcellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein.Isoform 2: Cell membrane; Single-pass type I membrane protein.Isoform 3: Cell membrane; Single-pass type I membrane protein.Isoform 4: Cell membrane; Single-pass type I membrane protein.Isoform 5: Cell membrane; Single-pass type I membrane protein.Isoform 7: Cytoplasm. | ||||||||||
Disease Associations | |||||||||||
Tissue Specificity | |||||||||||
Comments | |||||||||||
Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
|
||||||||||
Gene Ontology | |||||||||||
Molecular Function |
|
||||||||||
Biological Process |
|
||||||||||
Cellular Component |
|
||||||||||
Protein Structure and Domains | |||||||||||
PDB ID | |||||||||||
InterPro |
IPR001627
Sema domain IPR002165 Plexin IPR016201 Plexin-like fold |
||||||||||
PFAM |
PF01403
PF01437 |
||||||||||
PRINTS | |||||||||||
PIRSF | |||||||||||
SMART |
SM00630
SM00423 |
||||||||||
TIGRFAMs | |||||||||||
Post-translational Modifications | |||||||||||
Modification | |||||||||||
Cross-References | |||||||||||
SwissProt | Q8NFY4 | ||||||||||
PhosphoSite | PhosphoSite-Q8NFY4 | ||||||||||
TrEMBL | Q9HAH9 | ||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 80031 | ||||||||||
UniGene | Hs.594980 | ||||||||||
RefSeq | NP_705871 | ||||||||||
HUGO | HGNC:16770 | ||||||||||
OMIM | 609295 | ||||||||||
CCDS | CCDS32225 | ||||||||||
HPRD | 10221 | ||||||||||
IMGT | |||||||||||
EMBL | AB040912 AC009558 AC012050 AC018900 AC023905 AC044787 AC066615 AC084882 AF389426 AF389427 AF389428 AF389429 AF389430 AK021660 BC150253 | ||||||||||
GenPept | AAI50254 AAM69449 AAM69450 AAM69451 AAM69452 AAM69453 BAA96003 BAB13869 | ||||||||||