InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CACNA1S

Summary

InnateDB Protein

IDBP-105699.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CACNA1S

Protein Name

calcium channel, voltage-dependent, L type, alpha 1S subunit

Synonyms

CACNL1A3; Cav1.1; CCHL1A3; HOKPP; HOKPP1; hypoPP; MHS5; TTPP1;

Species

Homo sapiens

Ensembl Protein

ENSP00000356307

InnateDB Gene

IDBG-105693 (CACNA1S)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005245	voltage-gated calcium channel activity

Biological Process

GO:0006811	ion transport
GO:0034765	regulation of ion transmembrane transport
GO:0055085	transmembrane transport
GO:0070588	calcium ion transmembrane transport

Cellular Component

GO:0005891	voltage-gated calcium channel complex
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR002077 Voltage-dependent calcium channel, alpha-1 subunit
IPR005446 Voltage-dependent calcium channel, L-type, alpha-1 subunit
IPR005450 Voltage-dependent calcium channel, L-type, alpha-1S subunit
IPR005821 Ion transport domain
IPR013122 Polycystin cation channel, PKD1/PKD2
IPR014873 Voltage-dependent calcium channel, alpha-1 subunit, IQ domain

PFAM

PF00520
PF08016
PF08763

PRINTS

PR00167
PR01630
PR01634

PIRSF

SMART

SM01062

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt