Version 5.4
Homo sapiens Protein: FMOD
Summary
InnateDB Protein IDBP-105952.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FMOD
Protein Name fibromodulin
Synonyms FM; SLRR2E;
Species Homo sapiens
Ensembl Protein ENSP00000347041
InnateDB Gene IDBG-105950 (FMOD)
Protein Structure
UniProt Annotation
Function Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity). {ECO:0000250}.
Subcellular Localization Secreted, extracellular space, extracellular matrix.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0007181 transforming growth factor beta receptor complex assembly
GO:0018146 keratan sulfate biosynthetic process
GO:0030198 extracellular matrix organization
GO:0030203 glycosaminoglycan metabolic process
GO:0042339 keratan sulfate metabolic process
GO:0042340 keratan sulfate catabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
GO:0005796 Golgi lumen
GO:0031012 extracellular matrix
GO:0043202 lysosomal lumen
Protein Structure and Domains
PDB ID
InterPro IPR000372 Leucine-rich repeat-containing N-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
PFAM PF01462
PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00013
SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q06828
PhosphoSite PhosphoSite-
TrEMBL Q12833
UniProt Splice Variant
Entrez Gene 2331
UniGene Hs.722829
RefSeq NP_002014
HUGO HGNC:3774
OMIM 600245
CCDS CCDS30976
HPRD 02591
IMGT
EMBL AK291632 AK303866 AL359837 BC035281 CH471067 U05291 X72913 X75546
GenPept AAA16153 AAH35281 BAF84321 BAG64805 CAA51418 CAA53233 CAH73821 EAW91477 EAW91478

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca