Homo sapiens Protein: PRELP
Summary
InnateDB Protein IDBP-105957.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRELP
Protein Name proline/arginine-rich end leucine-rich repeat protein
Synonyms MST161; MSTP161; SLRR2A;
Species Homo sapiens
Ensembl Protein ENSP00000343924
InnateDB Gene IDBG-105955 (PRELP)
Protein Structure
UniProt Annotation
Function May anchor basement membranes to the underlying connective tissue. {ECO:0000250}.
Subcellular Localization Secreted, extracellular space, extracellular matrix.
Disease Associations
Tissue Specificity Connective tissue.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005201 extracellular matrix structural constituent
GO:0005515 protein binding
GO:0008201 heparin binding
Biological Process
GO:0001501 skeletal system development
GO:0005975 carbohydrate metabolic process
GO:0007569 cell aging
GO:0018146 keratan sulfate biosynthetic process
GO:0030203 glycosaminoglycan metabolic process
GO:0042339 keratan sulfate metabolic process
GO:0042340 keratan sulfate catabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005796 Golgi lumen
GO:0031012 extracellular matrix
GO:0043202 lysosomal lumen
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000372 Leucine-rich repeat-containing N-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
PFAM PF01462
PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00013
SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P51888
PhosphoSite PhosphoSite-P51888
TrEMBL Q7Z4B2
UniProt Splice Variant
Entrez Gene 5549
UniGene Hs.632481
RefSeq NP_958505
HUGO HGNC:9357
OMIM 601914
CCDS CCDS1438
HPRD 03556
IMGT
EMBL AF190164 AL391817 BC032498 CH471067 CR542270 U29089 U41343 U41344
GenPept AAC18782 AAC50230 AAH32498 AAQ13708 CAG47066 CAI17033 EAW91481