Version 5.4
Homo sapiens Protein: IL19
Summary
InnateDB Protein IDBP-106277.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL19
Protein Name interleukin 19
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000343000
InnateDB Gene IDBG-106273 (IL19)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 1 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
Biological Process
GO:0006915 apoptotic process
GO:0006955 immune response
GO:0007165 signal transduction
GO:0042226 interleukin-6 biosynthetic process
GO:0045087 innate immune response (InnateDB)
GO:0072593 reactive oxygen species metabolic process
GO:2001235 positive regulation of apoptotic signaling pathway
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro IPR009079 Four-helical cytokine-like, core
IPR020421 Interleukin-19
IPR020443 Interleukin-10/19/20/24/26 family
IPR020444 Interleukin-24
PFAM PF00726
PRINTS PR01934
PR01937
PIRSF
SMART SM00188
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UHD0
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 29949
UniGene Hs.661017
RefSeq NP_715639
HUGO HGNC:5990
OMIM 605687
CCDS CCDS1468
HPRD 05747
IMGT
EMBL AF192498 AF276915 AF390905 AF453946 AL049615 AL513315 AY040367
GenPept AAF06663 AAG16755 AAK64498 AAK91776 AAN40906 CAB72342 CAH71814

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca