Version 5.4
Homo sapiens Protein: CAPN9
Summary
InnateDB Protein IDBP-107372.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CAPN9
Protein Name calpain 9
Synonyms GC36; nCL-4;
Species Homo sapiens
Ensembl Protein ENSP00000346538
InnateDB Gene IDBG-107366 (CAPN9)
Protein Structure
UniProt Annotation
Function Calcium-regulated non-lysosomal thiol-protease.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed predominantly in stomach.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004198 calcium-dependent cysteine-type endopeptidase activity
GO:0005509 calcium ion binding
Biological Process
GO:0006508 proteolysis
GO:0007586 digestion
Cellular Component
GO:0005575 cellular_component
GO:0005622 intracellular
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001300 Peptidase C2, calpain, catalytic domain
IPR002048 EF-hand domain
IPR022682 Peptidase C2, calpain, large subunit, domain III
IPR022683 Peptidase C2, calpain, domain III
IPR022684 Peptidase C2, calpain family
PFAM PF00648
PF00036
PF13202
PF13405
PF01067
PRINTS PR00704
PIRSF
SMART SM00230
SM00054
SM00720
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O14815
PhosphoSite PhosphoSite-O14815
TrEMBL
UniProt Splice Variant
Entrez Gene 10753
UniGene Hs.498021
RefSeq NP_057536
HUGO HGNC:1486
OMIM 606401
CCDS CCDS31053
HPRD 05909
IMGT
EMBL AB038463 AF022799 AL512328 AY874864 FO393421
GenPept AAB80762 AAW49735 BAA92137

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca