Version 5.4
Homo sapiens Protein: SPRTN
Summary
InnateDB Protein IDBP-107424.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPRTN
Protein Name chromosome 1 open reading frame 124
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000008440
InnateDB Gene IDBG-107422 (SPRTN)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 91 experimentally validated interaction(s) in this database.
Experimentally validated
Total 91 [view]
Protein-Protein 90 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0043130 ubiquitin binding
GO:0046872 metal ion binding
GO:0070530 K63-linked polyubiquitin binding
Biological Process
GO:0006974 cellular response to DNA damage stimulus
GO:0009411 response to UV
GO:0019985 translesion synthesis
GO:0031398 positive regulation of protein ubiquitination
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0016607 nuclear speck
Protein Structure and Domains
PDB ID
InterPro IPR006640 Domain of unknown function SprT-like
PFAM PF10263
PRINTS
PIRSF
SMART SM00731
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H040
PhosphoSite PhosphoSite-Q9H040
TrEMBL
UniProt Splice Variant
Entrez Gene 83932
UniGene Hs.623990
RefSeq NP_001248391
HUGO HGNC:25356
OMIM
CCDS CCDS58066
HPRD 13164
IMGT
EMBL AK027317 AK027613 AL117352 AL512744 AY358611 BC015740 BC068478 CH471098
GenPept AAH15740 AAH68478 AAQ88974 BAB55037 BAB55232 CAC21670 EAW69956

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca