Homo sapiens Protein: CEP170
Summary
InnateDB Protein IDBP-107735.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CEP170
Protein Name centrosomal protein 170kDa
Synonyms FAM68A; KAB; KIAA0470;
Species Homo sapiens
Ensembl Protein ENSP00000355502
InnateDB Gene IDBG-107733 (CEP170)
Protein Structure
UniProt Annotation
Function Plays a role in microtubule organization. {ECO:0000269PubMed:15616186}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269PubMed:15616186}. Cytoplasm, cytoskeleton, spindle {ECO:0000269PubMed:15616186}. Note=Associated with the mature mother centriole. Associated with spindle microtubules during mitosis.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 29 [view]
Protein-Protein 29 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005814 centriole
GO:0005819 spindle
GO:0005874 microtubule
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID
InterPro IPR000253 Forkhead-associated (FHA) domain
IPR003961 Fibronectin, type III
IPR008984 SMAD/FHA domain
PFAM PF00498
PF00041
PF01108
PRINTS
PIRSF
SMART SM00240
SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5SW79
PhosphoSite PhosphoSite-Q5SW79
TrEMBL Q9NSN9
UniProt Splice Variant
Entrez Gene 9859
UniGene Hs.733787
RefSeq NP_001035863
HUGO HGNC:28920
OMIM 613023
CCDS CCDS44337
HPRD 17172
IMGT
EMBL AB007939 AB022657 AB022658 AB022659 AC092782 AL161964 AL606534 BC050722
GenPept AAH50722 BAA32315 BAA83378 BAA83379 BAA83380 CAB82309 CAI12943 CAI12944 CAI12945