Version 5.4
Homo sapiens Protein: CEP170
Summary
InnateDB Protein IDBP-107737.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CEP170
Protein Name centrosomal protein 170kDa
Synonyms FAM68A; KAB; KIAA0470;
Species Homo sapiens
Ensembl Protein ENSP00000355501
InnateDB Gene IDBG-107733 (CEP170)
Protein Structure
UniProt Annotation
Function Plays a role in microtubule organization. {ECO:0000269PubMed:15616186}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269PubMed:15616186}. Cytoplasm, cytoskeleton, spindle {ECO:0000269PubMed:15616186}. Note=Associated with the mature mother centriole. Associated with spindle microtubules during mitosis.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 29 [view]
Protein-Protein 29 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005814 centriole
GO:0005819 spindle
GO:0005874 microtubule
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID
InterPro IPR000253 Forkhead-associated (FHA) domain
IPR003961 Fibronectin, type III
IPR008984 SMAD/FHA domain
PFAM PF00498
PF00041
PF01108
PRINTS
PIRSF
SMART SM00240
SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5SW79
PhosphoSite PhosphoSite-Q5SW79
TrEMBL Q9NSN9
UniProt Splice Variant
Entrez Gene 9859
UniGene Hs.733787
RefSeq NP_001035864
HUGO HGNC:28920
OMIM 613023
CCDS CCDS44338
HPRD 17172
IMGT
EMBL AB007939 AB022657 AB022658 AB022659 AC092782 AL161964 AL606534 BC050722
GenPept AAH50722 BAA32315 BAA83378 BAA83379 BAA83380 CAB82309 CAI12943 CAI12944 CAI12945

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca