InnateDB Protein
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IDBP-11068.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PRSS21
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Protein Name
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protease, serine, 21 (testisin)
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Synonyms
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ESP-1; ESP1; TEST1; TESTISIN;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000005995
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InnateDB Gene
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IDBG-11066 (PRSS21)
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Protein Structure
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|
Function |
Could regulate proteolytic events associated with testicular germ cell maturation.
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Subcellular Localization |
Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Expressed predominantly in premeiotic testicular germ cells, mostly late pachytene and diplotene spermatocytes.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
7
[view]
|
Protein-Protein |
7
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001254
Peptidase S1
IPR001314
Peptidase S1A, chymotrypsin-type
IPR009003
Trypsin-like cysteine/serine peptidase domain
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PFAM |
PF00089
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PRINTS |
PR00722
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PIRSF |
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SMART |
SM00020
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TIGRFAMs |
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Modification |
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SwissProt |
Q9Y6M0
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PhosphoSite |
PhosphoSite-Q9Y6M0
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
10942
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UniGene |
|
RefSeq |
NP_659205
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HUGO |
HGNC:9485
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OMIM |
608159
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CCDS |
CCDS10478
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HPRD |
07082
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IMGT |
|
EMBL |
AB031329
AB031330
AB031331
AF058300
AF058301
AY359034
BC074999
BC075000
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GenPept |
AAD41588
AAF79019
AAF79020
AAH74999
AAH75000
AAQ89393
BAA83520
BAA83521
BAA89532
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