Version 5.4
Homo sapiens Protein: LCORL
Summary
InnateDB Protein IDBP-11195.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LCORL
Protein Name ligand dependent nuclear receptor corepressor-like
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000371661
InnateDB Gene IDBG-11193 (LCORL)
Protein Structure
UniProt Annotation
Function May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3'. May play a role in spermatogenesis (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00320}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR007889 DNA binding HTH domain, Psq-type
IPR009057 Homeodomain-like
PFAM PF04218
PF05225
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N3X6
PhosphoSite PhosphoSite-Q8N3X6
TrEMBL C9JI46
UniProt Splice Variant
Entrez Gene 254251
UniGene Hs.608423
RefSeq NP_001159611
HUGO HGNC:30776
OMIM 611799
CCDS CCDS54749
HPRD 10088
IMGT
EMBL AC005768 AC079399 AK055258 BC037322 CH471069
GenPept AAH37322 BAB70892 EAW92786 EAW92787

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca