Version 5.4
Mus musculus Protein: Arhgap12
Summary
InnateDB Protein IDBP-127922.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arhgap12
Protein Name Rho GTPase activating protein 12
Synonyms 2810011M08Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000054209
InnateDB Gene IDBG-127920 (Arhgap12)
Protein Structure
UniProt Annotation
Function GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID MGI:1922665
InterPro IPR000198 Rho GTPase-activating protein domain
IPR001202 WW domain
IPR001452 SH3 domain
IPR001849 Pleckstrin homology domain
IPR008936 Rho GTPase activation protein
PFAM PF00620
PF00397
PF00018
PF14604
PF00169
PRINTS PR00452
PIRSF
SMART SM00324
SM00456
SM00326
SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q8C0D4
TrEMBL Q8R1F4
UniProt Splice Variant
Entrez Gene 75415
UniGene Mm.413321
RefSeq
MGI ID
MGI Symbol Arhgap12
OMIM
CCDS
HPRD
IMGT
EMBL BC024633
GenPept AAH24633

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca