Mus musculus Gene: Arhgap12
Summary
InnateDB Gene IDBG-127920.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arhgap12
Gene Name Rho GTPase activating protein 12
Synonyms 2810011M08Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000041225
Encoded Proteins
Rho GTPase activating protein 12
Rho GTPase activating protein 12
Rho GTPase activating protein 12
Rho GTPase activating protein 12
Rho GTPase activating protein 12
Rho GTPase activating protein 12
Rho GTPase activating protein 12
Rho GTPase activating protein 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165322:
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may be involved in suppressing tumor formation by regulating cell invasion and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:6024427-6136098
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000062584 ENSMUSP00000054209
ENSMUST00000077128 ENSMUSP00000076376
ENSMUST00000182066 ENSMUSP00000138496
ENSMUST00000182213 ENSMUSP00000138464
ENSMUST00000182559 ENSMUSP00000138585
ENSMUST00000182383 ENSMUSP00000138444
ENSMUST00000182343
ENSMUST00000182101
ENSMUST00000182921 ENSMUSP00000138798
ENSMUST00000182614
ENSMUST00000182322
ENSMUST00000182038 ENSMUSP00000138150
ENSMUST00000181989
ENSMUST00000182178
ENSMUST00000182572
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005096 GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0002011 morphogenesis of an epithelial sheet
GO:0007165 signal transduction
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005622 intracellular
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Signaling by Rho GTPases pathway
Rho GTPase cycle pathway
Signal Transduction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Rho GTPase cycle pathway
Signaling by Rho GTPases pathway
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001039692 NM_029277 XM_006526314 XM_006526315
OMIM
CCDS CCDS37722 CCDS37723
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas