InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ighmbp2

Summary

InnateDB Protein

IDBP-128155.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ighmbp2

Protein Name

immunoglobulin mu binding protein 2

Synonyms

AEP; Catf1; nmd; RIPE3b1; sma; Smbp-2; Smbp2; Smubp2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000025751

InnateDB Gene

IDBG-128153 (Ighmbp2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	10 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000049	tRNA binding
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008094	DNA-dependent ATPase activity
GO:0008134	transcription factor binding
GO:0008186	RNA-dependent ATPase activity
GO:0008270	zinc ion binding
GO:0016787	hydrolase activity
GO:0017111	nucleoside-triphosphatase activity
GO:0032575	ATP-dependent 5'-3' RNA helicase activity
GO:0043022	ribosome binding
GO:0043141	ATP-dependent 5'-3' DNA helicase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0032508	DNA duplex unwinding
GO:0051260	protein homooligomerization

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0016020	membrane
GO:0032797	SMN complex

Protein Structure and Domains

PDB ID

MGI:99954

InterPro

IPR000058 Zinc finger, AN1-type
IPR001374 Single-stranded nucleic acid binding R3H
IPR003593 AAA+ ATPase domain
IPR004483 Helicase SMUBP-2/Hcs1-like
IPR006935 Helicase/UvrB domain
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF01428
PF01424
PF04851

PRINTS

PIRSF

SMART

SM00154
SM00393
SM00382
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite