Version 5.4
Mus musculus Gene: Ighmbp2
Summary
InnateDB Gene IDBG-128153.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ighmbp2
Gene Name immunoglobulin mu binding protein 2
Synonyms AEP; Catf1; nmd; RIPE3b1; sma; Smbp-2; Smbp2; Smubp2
Species Mus musculus
Ensembl Gene ENSMUSG00000024831
Encoded Proteins
IDBP-128155
immunoglobulin mu binding protein 2
IDBP-401775
immunoglobulin mu binding protein 2
IDBP-541094
immunoglobulin mu binding protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132740:
This gene encodes a helicase superfamily member that binds a specific DNA sequence from the immunoglobulin mu chain switch region. Mutations in this gene lead to spinal muscle atrophy with respiratory distress type 1. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:3260924-3283017
Strand Reverse strand
Band A
Transcripts
ENSMUST00000025751 ENSMUSP00000025751
ENSMUST00000119292 ENSMUSP00000113438
ENSMUST00000154537 ENSMUSP00000122827
ENSMUST00000143079
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 10 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008094 DNA-dependent ATPase activity
GO:0008134 transcription factor binding
GO:0008186 RNA-dependent ATPase activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0017111 nucleoside-triphosphatase activity
GO:0032575 ATP-dependent 5'-3' RNA helicase activity
GO:0043022 ribosome binding
GO:0043141 ATP-dependent 5'-3' DNA helicase activity
Biological Process
GO:0006200 ATP catabolic process
GO:0008152 metabolic process
GO:0021522 spinal cord motor neuron differentiation
GO:0032508 DNA duplex unwinding
GO:0051260 protein homooligomerization
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0032797 SMN complex
GO:0043025 neuronal cell body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000132740
View Gene Order
ENSBTAG00000022185
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.3179 Mm.397321
RefSeq NM_009212 XM_006531701
OMIM
CCDS CCDS29393
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca