Version 5.4
Mus musculus Protein: Cetn1
Summary
InnateDB Protein IDBP-128231.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cetn1
Protein Name centrin 1
Synonyms caltractin;
Species Mus musculus
Ensembl Protein ENSMUSP00000057392
InnateDB Gene IDBG-128229 (Cetn1)
Protein Structure
UniProt Annotation
Function Plays a fundamental role in microtubule-organizing center structure and function.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Centrosome of interphase and mitotic cells.
Disease Associations
Tissue Specificity Expressed exclusively in testis. Localizes to the caudal portion of spermatozoa in seminiferous tubule and epididymis. {ECO:0000269PubMed:10486202}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008017 microtubule binding
GO:0008026 ATP-dependent helicase activity
GO:0031683 G-protein beta/gamma-subunit complex binding
GO:0032795 heterotrimeric G-protein binding
Biological Process
GO:0006200 ATP catabolic process
GO:0007067 mitotic nuclear division
GO:0034605 cellular response to heat
Cellular Component
GO:0000922 spindle pole
GO:0005813 centrosome
GO:0005814 centriole
GO:0032391 photoreceptor connecting cilium
Protein Structure and Domains
PDB ID MGI:1347086
InterPro IPR002048 EF-hand domain
PFAM PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P41209
PhosphoSite PhosphoSite-P41209
TrEMBL
UniProt Splice Variant
Entrez Gene 26369
UniGene Mm.195831
RefSeq NP_031619
MGI ID
MGI Symbol Cetn1
OMIM
CCDS CCDS37731
HPRD
IMGT
EMBL AF080591 AK005736 AK005743 AK005837 AK006940 AK015808 AK076986 AK132753 BC048488 BC061155 D16301
GenPept AAD46390 AAH48488 AAH61155 BAA03806 BAB24213 BAB24217 BAB24266 BAB24798 BAB29985 BAC36550 BAE21334

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca