Version 5.4
Mus musculus Gene: Cetn1
Summary
InnateDB Gene IDBG-128229.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cetn1
Gene Name centrin 1
Synonyms caltractin
Species Mus musculus
Ensembl Gene ENSMUSG00000050996
Encoded Proteins
IDBP-128231
centrin 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000177143:
The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This encoded protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:9615524-9619478
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000062769 ENSMUSP00000057392
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008017 microtubule binding
GO:0008026 ATP-dependent helicase activity
GO:0031683 G-protein beta/gamma-subunit complex binding
GO:0032795 heterotrimeric G-protein binding
Biological Process
GO:0006200 ATP catabolic process
GO:0007067 mitotic nuclear division
GO:0034605 cellular response to heat
Cellular Component
GO:0000922 spindle pole
GO:0005813 centrosome
GO:0005814 centriole
GO:0032391 photoreceptor connecting cilium
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000177143
View Gene Order
ENSBTAG00000012320
Not yet available
Cross-References
SwissProt P41209
TrEMBL
UniProt Splice Variant
Entrez Gene 26369
UniGene Mm.195831
RefSeq NM_007593
OMIM
CCDS CCDS37731
HPRD
IMGT
MGI ID MGI:1347086
MGI Symbol Cetn1
EMBL AF080591 AK005736 AK005743 AK005837 AK006940 AK015808 AK076986 AK132753 BC048488 BC061155 D16301
GenPept AAD46390 AAH48488 AAH61155 BAA03806 BAB24213 BAB24217 BAB24266 BAB24798 BAB29985 BAC36550 BAE21334
RNA Seq Atlas 26369

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca