InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sdc1

Summary

InnateDB Protein

IDBP-128468.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sdc1

Protein Name

syndecan 1

Synonyms

AA408134; AA409076; CD138; Sstn; syn-1; Synd; Synd1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000020911

InnateDB Gene

IDBG-128466 (Sdc1)

Protein Structure

UniProt Annotation

Function

Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.

Subcellular Localization

Membrane; Single-pass type I membrane protein. Secreted. Note=Shedding of the ectodomain produces a soluble form.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001948	glycoprotein binding
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0008092	cytoskeletal protein binding

Biological Process

GO:0001657	ureteric bud development
GO:0006954	inflammatory response
GO:0009636	response to toxic substance
GO:0010033	response to organic substance
GO:0042060	wound healing
GO:0042476	odontogenesis
GO:0042542	response to hydrogen peroxide
GO:0048627	myoblast development
GO:0051384	response to glucocorticoid
GO:0051591	response to cAMP
GO:0051592	response to calcium ion
GO:0055002	striated muscle cell development
GO:0060009	Sertoli cell development
GO:0060070	canonical Wnt signaling pathway

Cellular Component

GO:0005576	extracellular region
GO:0005737	cytoplasm
GO:0005796	Golgi lumen
GO:0005925	focal adhesion
GO:0009897	external side of plasma membrane
GO:0009986	cell surface
GO:0016021	integral component of membrane
GO:0043234	protein complex
GO:0070062	extracellular vesicular exosome