Version 5.4
Mus musculus Protein: Thsd7a
Summary
InnateDB Protein IDBP-128565.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Thsd7a
Protein Name thrombospondin, type I, domain containing 7A
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000040176
InnateDB Gene IDBG-128563 (Thsd7a)
Protein Structure
UniProt Annotation
Function The soluble form promotes endothelial cell migration and filopodia formationduring angiogenesis via a FAK-dependent mechanism. {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Single-pass type I membrane protein. Secreted {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0001525 angiogenesis
GO:0008150 biological_process
GO:0030154 cell differentiation
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:2685683
InterPro IPR000884 Thrombospondin, type 1 repeat
PFAM PF00090
PRINTS
PIRSF
SMART SM00209
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q69ZU6
PhosphoSite PhosphoSite-Q69ZU6
TrEMBL E9Q6P0
UniProt Splice Variant
Entrez Gene 330267
UniGene Mm.11989
RefSeq NP_001158277
MGI ID
MGI Symbol Thsd7a
OMIM
CCDS CCDS51721
HPRD
IMGT
EMBL AC122394 AC124006 AC154026 AC157024 AK136087 AK164834 AK173072
GenPept BAD32350 BAE22813 BAE37936

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca