Version 5.4
Mus musculus Gene: Thsd7a
Summary
InnateDB Gene IDBG-128563.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Thsd7a
Gene Name thrombospondin, type I, domain containing 7A
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000032625
Encoded Proteins
IDBP-128565
thrombospondin, type I, domain containing 7A
IDBP-401697
thrombospondin, type I, domain containing 7A
IDBP-401696
thrombospondin, type I, domain containing 7A
IDBP-401695
thrombospondin, type I, domain containing 7A
IDBP-623498
thrombospondin, type I, domain containing 7A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000005108:
The protein encoded by this gene is found almost exclusively in endothelial cells from placenta and umbilical cord. The encoded protein appears to interact with alpha(V)beta(3) integrin and paxillin to inhibit endothelial cell migration and tube formation. This protein may be involved in cytoskeletal organization. Variations in this gene may be associated with low bone mineral density in osteoporosis. [provided by RefSeq, Aug 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:12311610-12749410
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000046121 ENSMUSP00000040176
ENSMUST00000119581 ENSMUSP00000113681
ENSMUST00000122369 ENSMUSP00000112503
ENSMUST00000119443 ENSMUSP00000113780
ENSMUST00000137836
ENSMUST00000135450
ENSMUST00000172356 ENSMUSP00000131662
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0001525 angiogenesis
GO:0008150 biological_process
GO:0030154 cell differentiation
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000005108
View Gene Order
ENSBTAG00000007680
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22161
Post-translational protein modification pathway
REACT_200727
O-linked glycosylation pathway
REACT_17015
Metabolism of proteins pathway
REACT_200626
O-glycosylation of TSR domain-containing proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E9PWD2
UniProt Splice Variant
Entrez Gene 330267
UniGene Mm.11989
RefSeq NM_001164805 XM_006505123
OMIM
CCDS CCDS51721
HPRD
IMGT
MGI ID MGI:2685683
MGI Symbol Thsd7a
EMBL AC122394 AC124006 AC154026 AC157024
GenPept
RNA Seq Atlas 330267

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca