Version 5.4
Mus musculus Protein: Car8
Summary
InnateDB Protein IDBP-128816.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Car8
Protein Name carbonic anhydrase 8
Synonyms AW546993; Ca8; Cals; Cals1; Carp; wdl;
Species Mus musculus
Ensembl Protein ENSMUSP00000063511
InnateDB Gene IDBG-128812 (Car8)
Protein Structure
UniProt Annotation
Function Does not have a carbonic anhydrase catalytic activity.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed only in Purkinje cells.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004089 carbonate dehydratase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0006730 one-carbon metabolic process
GO:0048015 phosphatidylinositol-mediated signaling
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:88253
InterPro IPR001148 Alpha carbonic anhydrase
PFAM PF00194
PRINTS
PIRSF
SMART SM01057
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P28651
PhosphoSite PhosphoSite-P28651
TrEMBL
UniProt Splice Variant
Entrez Gene 12319
UniGene Mm.119320
RefSeq NP_031618
MGI ID
MGI Symbol Car8
OMIM
CCDS CCDS17954
HPRD
IMGT
EMBL AK004896 BC010773 X61397
GenPept AAH10773 BAC25100 CAA43668

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca