InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Amacr

Summary

InnateDB Protein

IDBP-129544.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Amacr

Protein Name

alpha-methylacyl-CoA racemase

Synonyms

Macr1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000066915

InnateDB Gene

IDBG-129542 (Amacr)

Protein Structure

UniProt Annotation

Function

Racemization of 2-methyl-branched fatty acid CoA esters. Responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers.

Subcellular Localization

Peroxisome {ECO:0000269PubMed:10770938}. Mitochondrion {ECO:0000269PubMed:10770938}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0005102	receptor binding
GO:0008111	alpha-methylacyl-CoA racemase activity

Biological Process

GO:0006631	fatty acid metabolic process
GO:0006699	bile acid biosynthetic process
GO:0008152	metabolic process
GO:0008206	bile acid metabolic process
GO:0008300	isoprenoid catabolic process