InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ptprz1

Summary

InnateDB Protein

IDBP-129595.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Ptprz1

Protein Name

protein tyrosine phosphatase, receptor type Z, polypeptide 1

Synonyms

AI850339; DSD-1-PG; PTPbeta; Ptprz; Ptpz; PTPzeta; Rptpbeta; RPTPz;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000088056

InnateDB Gene

IDBG-129593 (Ptprz1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004725	protein tyrosine phosphatase activity
GO:0005515	protein binding
GO:0016791	phosphatase activity

Biological Process

GO:0002244	hematopoietic progenitor cell differentiation
GO:0006470	protein dephosphorylation
GO:0007409	axonogenesis
GO:0007611	learning or memory
GO:0016311	dephosphorylation
GO:0035335	peptidyl-tyrosine dephosphorylation
GO:0048709	oligodendrocyte differentiation
GO:0070445	regulation of oligodendrocyte progenitor proliferation

Cellular Component

GO:0005578	proteinaceous extracellular matrix
GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0072534	perineuronal net

Protein Structure and Domains

PDB ID

MGI:97816

InterPro

IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type
IPR000387 Protein-tyrosine/Dual specificity phosphatase
IPR001148 Alpha carbonic anhydrase
IPR003595 Protein-tyrosine phosphatase, catalytic
IPR003961 Fibronectin, type III
IPR029021 Protein-tyrosine phosphatase-like

PFAM

PF00102
PF00194
PF00041
PF01108

PRINTS

PR00700

PIRSF

SMART

SM00194
SM01057
SM00404
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt