Version 5.4
Mus musculus Protein: Ndufa5
Summary
InnateDB Protein IDBP-130089.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ndufa5
Protein Name NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
Synonyms 2900002J19Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000023851
InnateDB Gene IDBG-130087 (Ndufa5)
Protein Structure
UniProt Annotation
Function Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0016651 oxidoreductase activity, acting on NAD(P)H
Biological Process
GO:0022904 respiratory electron transport chain
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005747 mitochondrial respiratory chain complex I
GO:0045271 respiratory chain complex I
Protein Structure and Domains
PDB ID MGI:1915452
InterPro IPR006806 ETC complex I subunit
PFAM PF04716
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CPP6
PhosphoSite PhosphoSite-Q9CPP6
TrEMBL
UniProt Splice Variant
Entrez Gene 68202
UniGene
RefSeq NP_080890
MGI ID
MGI Symbol Ndufa5
OMIM
CCDS CCDS19942
HPRD
IMGT
EMBL AK008156 AK008286 AK008414 AK009338 AK009396 AK009461 AK009493 AK009608 AK009642 AK009652 AK009775 AK009840 AK009985 AK010024 AK010090 AK010092 AK011579 AK011947 AK019084 AK019201 AK019207 AK019215 AK019242 AK019245 AK019291 AK019301 AK019324 AK019354 AK019359 AK019364 AK019368 BC028633
GenPept AAH28633 BAB25499 BAB25577 BAB25655 BAB26226 BAB26263 BAB26302 BAB26323 BAB26389 BAB26409 BAB26416 BAB26496 BAB26535 BAB26627 BAB26649 BAB26695 BAB26696 BAB27713 BAB27932 BAB31537 BAB31598 BAB31601 BAB31606 BAB31622 BAB31624 BAB31650 BAB31656 BAB31667 BAB31675 BAB31678 BAB31681 BAB31682

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca