InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lgals8

Summary

InnateDB Protein

IDBP-130208.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lgals8

Protein Name

lectin, galactose binding, soluble 8

Synonyms

1200015E08Rik; AI326142; D13Ertd524e; Lgals-8;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000097408

InnateDB Gene

IDBG-130204 (Lgals8)

Protein Structure

UniProt Annotation

Function

Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans. {ECO:0000250}.

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0030246	carbohydrate binding

Biological Process

GO:0002317	plasma cell differentiation
GO:0031295	T cell costimulation

Cellular Component

GO:0005575	cellular_component
GO:0005737	cytoplasm
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1928481

InterPro

IPR001079 Galectin, carbohydrate recognition domain
IPR008985 Concanavalin A-like lectin/glucanases superfamily

PFAM

PF00337

PRINTS

PIRSF

SMART

SM00276
SM00908

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9JL15

PhosphoSite

PhosphoSite-Q9JL15

TrEMBL

Q8C6H0

UniProt Splice Variant

Entrez Gene

56048

UniGene

Mm.474138

RefSeq

XP_006516777

MGI ID

MGI Symbol

Lgals8

OMIM

CCDS

CCDS36592

HPRD

IMGT

EMBL

AC154221 AF218069 AK004782 AK029526 AK075736 AK083350 AK145881 AK146746 BC040243 CH466588 CT010251

GenPept

AAF27645 AAH40243 BAB23560 BAC26495 BAC35918 BAC38880 BAE26721 BAE27406 CAJ18459 EDL32308 EDL32309 EDL32310 EDL32312