Version 5.4
Mus musculus Protein: Dpp3
Summary
InnateDB Protein IDBP-130321.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dpp3
Protein Name dipeptidylpeptidase 3
Synonyms 4930533O14Rik; C86324;
Species Mus musculus
Ensembl Protein ENSMUSP00000025851
InnateDB Gene IDBG-130319 (Dpp3)
Protein Structure
UniProt Annotation
Function Cleaves and degrades of the opioid peptide enkephalin. Also cleaves Arg-Arg-beta-naphthylamide (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004177 aminopeptidase activity
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0008239 dipeptidyl-peptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1922471
InterPro IPR005317 Dipeptidyl-peptidase 3
PFAM
PRINTS
PIRSF PIRSF007828
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99KK7
PhosphoSite PhosphoSite-Q99KK7
TrEMBL Q3UDY7
UniProt Splice Variant
Entrez Gene 75221
UniGene Mm.234769
RefSeq NP_598564
MGI ID
MGI Symbol Dpp3
OMIM
CCDS CCDS29443
HPRD
IMGT
EMBL AK031020 AK149853 AK166842 BC004600
GenPept AAH04600 BAC27216 BAE29124 BAE39063

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca