Version 5.4
Mus musculus Protein: Pex2
Summary
InnateDB Protein IDBP-130411.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pex2
Protein Name peroxisomal membrane protein 3
Synonyms D3Ertd138e; PAF-1; PMP35; Pxmp3;
Species Mus musculus
Ensembl Protein ENSMUSP00000059415
InnateDB Gene IDBG-130409 (Pex2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0000038 very long-chain fatty acid metabolic process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001764 neuron migration
GO:0006635 fatty acid beta-oxidation
GO:0006699 bile acid biosynthetic process
GO:0007399 nervous system development
GO:0016558 protein import into peroxisome matrix
GO:0031648 protein destabilization
GO:0042632 cholesterol homeostasis
GO:0045540 regulation of cholesterol biosynthetic process
GO:0048147 negative regulation of fibroblast proliferation
GO:0050680 negative regulation of epithelial cell proliferation
Cellular Component
GO:0005779 integral component of peroxisomal membrane
GO:0016593 Cdc73/Paf1 complex
Protein Structure and Domains
PDB ID MGI:107486
InterPro IPR001841 Zinc finger, RING-type
IPR006845 Pex, N-terminal
PFAM PF13639
PF14634
PF04757
PRINTS
PIRSF
SMART SM00184
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q91YZ5
UniProt Splice Variant
Entrez Gene 19302
UniGene
RefSeq NP_001254644
MGI ID
MGI Symbol Pex2
OMIM
CCDS CCDS17228
HPRD
IMGT
EMBL AC119876 AK151121 AK152331 BC012404 CH466577
GenPept AAH12404 BAE30130 BAE31130 EDL05215

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca