InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tbce

Summary

InnateDB Protein

IDBP-131191.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tbce

Protein Name

tubulin-specific chaperone E

Synonyms

2610206D02Rik; C530005D02Rik; pmn;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000047880

InnateDB Gene

IDBG-131189 (Tbce)

Protein Structure

UniProt Annotation

Function

Tubulin-folding protein; involved in the second step of the tubulin folding pathway. Seems to be implicated in the maintenance of the neuronal microtubule network. Involved in regulation of tubulin heterodimer dissociation. {ECO:0000269PubMed:12389029, ECO:0000269PubMed:17184771}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.

Disease Associations

Tissue Specificity

Ubiquitously expressed. {ECO:0000269PubMed:12389029}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0051082	unfolded protein binding

Biological Process

GO:0000226	microtubule cytoskeleton organization
GO:0006457	protein folding
GO:0007021	tubulin complex assembly
GO:0007023	post-chaperonin tubulin folding pathway
GO:0007409	axonogenesis
GO:0008344	adult locomotory behavior
GO:0009791	post-embryonic development
GO:0014889	muscle atrophy
GO:0048589	developmental growth
GO:0048936	peripheral nervous system neuron axonogenesis