Mus musculus Gene: Tbce
Summary
InnateDB Gene IDBG-131189.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tbce
Gene Name tubulin-specific chaperone E
Synonyms 2610206D02Rik; C530005D02Rik; pmn
Species Mus musculus
Ensembl Gene ENSMUSG00000039233
Encoded Proteins
tubulin-specific chaperone E
tubulin-specific chaperone E
tubulin-specific chaperone E
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116957:
Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:13997949-14039638
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000039894 ENSMUSP00000047880
ENSMUST00000159893 ENSMUSP00000125244
ENSMUST00000160510
ENSMUST00000160553
ENSMUST00000162326 ENSMUSP00000125613
ENSMUST00000159239
ENSMUST00000159427
ENSMUST00000162241
ENSMUST00000161554
ENSMUST00000162440
ENSMUST00000159966
ENSMUST00000160304
ENSMUST00000160776
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0051082 unfolded protein binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0006457 protein folding
GO:0007021 tubulin complex assembly
GO:0007023 post-chaperonin tubulin folding pathway
GO:0007409 axonogenesis
GO:0008344 adult locomotory behavior
GO:0009791 post-embryonic development
GO:0014889 muscle atrophy
GO:0048589 developmental growth
GO:0048936 peripheral nervous system neuron axonogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Metabolism of proteins pathway
Post-chaperonin tubulin folding pathway pathway
Protein folding pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Post-chaperonin tubulin folding pathway pathway
Protein folding pathway
Metabolism of proteins pathway
Post-chaperonin tubulin folding pathway pathway
Metabolism of proteins pathway
Protein folding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.260209
RefSeq NM_178337 XM_006516774
OMIM
CCDS CCDS26247
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas