InnateDB Protein
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IDBP-131635.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Abat
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Protein Name
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4-aminobutyrate aminotransferase
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000063548
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InnateDB Gene
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IDBG-131633 (Abat)
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Protein Structure
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Function |
Catalyzes the conversion of gamma-aminobutyrate and L- beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine (By similarity). {ECO:0000250}.
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Subcellular Localization |
Mitochondrion matrix {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
4
[view]
|
Protein-Protein |
4
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
Accession |
GO Term |
GO:0003867
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4-aminobutyrate transaminase activity
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GO:0008483
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transaminase activity
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GO:0030170
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pyridoxal phosphate binding
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GO:0032145
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succinate-semialdehyde dehydrogenase binding
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GO:0042803
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protein homodimerization activity
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GO:0047298
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(S)-3-amino-2-methylpropionate transaminase activity
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2443582
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InterPro |
IPR004631
4-aminobutyrate aminotransferase, eukaryotic
IPR005814
Aminotransferase class-III
IPR015424
Pyridoxal phosphate-dependent transferase
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PFAM |
PF00202
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PRINTS |
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PIRSF |
PIRSF000521
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P61922
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PhosphoSite |
PhosphoSite-P61922
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
268860
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UniGene |
Mm.480038
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RefSeq |
NP_766549
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MGI ID |
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MGI Symbol |
Abat
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OMIM |
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CCDS |
CCDS27939
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HPRD |
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IMGT |
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EMBL |
AK036128
BC058079
BC058521
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GenPept |
AAH58079
AAH58521
BAC29312
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