InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc10a2

Summary

InnateDB Protein

IDBP-131725.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc10a2

Protein Name

solute carrier family 10, member 2

Synonyms

ASBT; ISBT;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000023835

InnateDB Gene

IDBG-131723 (Slc10a2)

Protein Structure

UniProt Annotation

Function

Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism (By similarity). {ECO:0000250}.

Subcellular Localization

Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008508	bile acid:sodium symporter activity

Biological Process

GO:0006814	sodium ion transport
GO:0015711	organic anion transport
GO:0015721	bile acid and bile salt transport
GO:0055085	transmembrane transport

Cellular Component

GO:0000502	proteasome complex
GO:0005634	nucleus
GO:0005902	microvillus
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane