InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cyp7b1

Summary

InnateDB Protein

IDBP-132339.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cyp7b1

Protein Name

cytochrome P450, family 7, subfamily b, polypeptide 1

Synonyms

AW261589; D3Ertd552e; hct-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000037487

InnateDB Gene

IDBG-132337 (Cyp7b1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Disease Associations

Tissue Specificity

Highly expressed in brain; also expressed in liver and kidney.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005506	iron ion binding
GO:0008396	oxysterol 7-alpha-hydroxylase activity
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037	heme binding
GO:0033783	25-hydroxycholesterol 7alpha-hydroxylase activity

Biological Process

GO:0006699	bile acid biosynthetic process
GO:0007586	digestion
GO:0008203	cholesterol metabolic process
GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway
GO:0050679	positive regulation of epithelial cell proliferation
GO:0055114	oxidation-reduction process
GO:0060740	prostate gland epithelium morphogenesis