Mus musculus Gene: Cyp7b1 | |||||||||||||||
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Summary | |||||||||||||||
InnateDB Gene | IDBG-132337.6 | ||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
Gene Symbol | Cyp7b1 | ||||||||||||||
Gene Name | cytochrome P450, family 7, subfamily b, polypeptide 1 | ||||||||||||||
Synonyms | AW261589; D3Ertd552e; hct-1 | ||||||||||||||
Species | Mus musculus | ||||||||||||||
Ensembl Gene | ENSMUSG00000039519 | ||||||||||||||
Encoded Proteins |
cytochrome P450, family 7, subfamily b, polypeptide 1
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Protein Structure | |||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
Entrez Gene | |||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000172817:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||
Type | Protein coding | ||||||||||||||
Genomic Location | Chromosome 3:18071950-18243338 | ||||||||||||||
Strand | Reverse strand | ||||||||||||||
Band | A1 | ||||||||||||||
Transcripts |
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Interactions | |||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||
NETPATH | |||||||||||||||
REACTOME |
Cytochrome P450 - arranged by substrate type pathway
Phase 1 - Functionalization of compounds pathway
Orphan transporters pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Endogenous sterols pathway
Synthesis of bile acids and bile salts pathway
Transmembrane transport of small molecules pathway
Biological oxidations pathway
Synthesis of bile acids and bile salts via 27-hydroxycholesterol pathway
Bile acid and bile salt metabolism pathway
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KEGG |
Primary bile acid biosynthesis pathway
Steroid hormone biosynthesis pathway
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INOH | |||||||||||||||
PID NCI | |||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||
NETPATH | |||||||||||||||
REACTOME |
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol pathway
Synthesis of bile acids and bile salts via 27-hydroxycholesterol pathway
Synthesis of bile acids and bile salts pathway
Endogenous sterols pathway
Transmembrane transport of small molecules pathway
Metabolism of lipids and lipoproteins pathway
Bile acid and bile salt metabolism pathway
Cytochrome P450 - arranged by substrate type pathway
Orphan transporters pathway
Metabolism pathway
Biological oxidations pathway
Phase 1 - Functionalization of compounds pathway
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KEGG |
Steroid hormone biosynthesis pathway
Primary bile acid biosynthesis pathway
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INOH | |||||||||||||||
PID NCI | |||||||||||||||
Cross-References | |||||||||||||||
SwissProt | |||||||||||||||
TrEMBL | |||||||||||||||
UniProt Splice Variant | |||||||||||||||
Entrez Gene | |||||||||||||||
UniGene | Mm.316000 | ||||||||||||||
RefSeq | NM_007825 XM_006535383 | ||||||||||||||
OMIM | |||||||||||||||
CCDS | CCDS17254 | ||||||||||||||
HPRD | |||||||||||||||
IMGT | |||||||||||||||
MGI ID | |||||||||||||||
MGI Symbol | |||||||||||||||
EMBL | |||||||||||||||
GenPept | |||||||||||||||
RNA Seq Atlas | |||||||||||||||