InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Amph

Summary

InnateDB Protein

IDBP-132342.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Amph

Protein Name

amphiphysin

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000003345

InnateDB Gene

IDBG-132340 (Amph)

Protein Structure

UniProt Annotation

Function

May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	40 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005543	phospholipid binding

Biological Process

GO:0007612	learning
GO:0048488	synaptic vesicle endocytosis

Cellular Component

GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0008021	synaptic vesicle
GO:0030054	cell junction
GO:0030672	synaptic vesicle membrane
GO:0031256	leading edge membrane