Version 5.4
Mus musculus Protein: Scaf8
Summary
InnateDB Protein IDBP-132409.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Scaf8
Protein Name SR-related CTD-associated factor 8
Synonyms A630086M08Rik; A930036P18Rik; AA408306; AI447644; AI448652; AU015035; mKIAA1116; Rbm16;
Species Mus musculus
Ensembl Protein ENSMUSP00000076024
InnateDB Gene IDBG-132405 (Scaf8)
Protein Structure
UniProt Annotation
Function May play a role in mRNA processing. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000269PubMed:9528809}. Nucleus matrix {ECO:0000269PubMed:9528809}. Note=Detected in granular nuclear foci which correspond to sites of active transcription.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0043175 RNA polymerase core enzyme binding
Biological Process
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0016363 nuclear matrix
Protein Structure and Domains
PDB ID MGI:1925212
InterPro IPR000504 RNA recognition motif domain
IPR006569 CID domain
IPR006903 RNA polymerase II-binding domain
IPR008942 ENTH/VHS
PFAM PF00076
PF04818
PRINTS
PIRSF
SMART SM00360
SM00582
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6DID3
PhosphoSite PhosphoSite-Q6DID3
TrEMBL Q99LN2
UniProt Splice Variant
Entrez Gene 106583
UniGene Mm.124373
RefSeq NP_598884
MGI ID
MGI Symbol Scaf8
OMIM
CCDS CCDS49927
HPRD
IMGT
EMBL AK032418 AK122451 AK161113 BC002302 BC038363 BC075621
GenPept AAH02302 AAH38363 AAH75621 BAC27860 BAC65733 BAE36197

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca