Version 5.4
Mus musculus Protein: Sipa1
Summary
InnateDB Protein IDBP-132417.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sipa1
Protein Name signal-induced proliferation associated gene 1
Synonyms Spa1;
Species Mus musculus
Ensembl Protein ENSMUSP00000073618
InnateDB Gene IDBG-132413 (Sipa1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
Biological Process
GO:0042631 cellular response to water deprivation
GO:0043547 positive regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0051726 regulation of cell cycle
Cellular Component
GO:0030133 transport vesicle
GO:0043234 protein complex
Protein Structure and Domains
PDB ID MGI:107576
InterPro IPR000331 Rap GTPase activating protein domain
IPR001478 PDZ domain
PFAM PF02145
PF00595
PF13180
PRINTS
PIRSF
SMART SM00228
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3V403
UniProt Splice Variant
Entrez Gene 20469
UniGene Mm.3072
RefSeq NP_001157953
MGI ID
MGI Symbol Sipa1
OMIM
CCDS CCDS29474
HPRD
IMGT
EMBL AC134563 AK028151
GenPept BAE20437

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca