InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nmt2

Summary

InnateDB Protein

IDBP-133006.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nmt2

Protein Name

N-myristoyltransferase 2

Synonyms

A930001K02Rik; AI605445; AU044698; hNMT-2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000080600

InnateDB Gene

IDBG-133000 (Nmt2)

Protein Structure

UniProt Annotation

Function

Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004379	glycylpeptide N-tetradecanoyltransferase activity

Biological Process

GO:0006499	N-terminal protein myristoylation
GO:0018008	N-terminal peptidyl-glycine N-myristoylation

Cellular Component

GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane

Protein Structure and Domains

PDB ID

MGI:1202298

InterPro

IPR000903 Myristoyl-CoA:protein N-myristoyltransferase
IPR016181 Acyl-CoA N-acyltransferase
IPR022676 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal
IPR022677 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal

PFAM

PF01233
PF02799

PRINTS

PIRSF

PIRSF015892

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O70311