Mus musculus Gene: Nmt2
Summary
InnateDB Gene IDBG-133000.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nmt2
Gene Name N-myristoyltransferase 2
Synonyms A930001K02Rik; AI605445; AU044698; hNMT-2
Species Mus musculus
Ensembl Gene ENSMUSG00000026643
Encoded Proteins
N-myristoyltransferase 2
N-myristoyltransferase 2
N-myristoyltransferase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000152465:
N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77% and 96% sequence identity with human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases. [provided by RefSeq, Jul 2008]
N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein\'s N-terminal glycine residue. Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77%% and 96%% sequence identity with human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:3284212-3328877
Strand Forward strand
Band A1
Transcripts
ENSMUST00000102989 ENSMUSP00000100054
ENSMUST00000091504 ENSMUSP00000089085
ENSMUST00000081932 ENSMUSP00000080600
ENSMUST00000155761
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004379 glycylpeptide N-tetradecanoyltransferase activity
Biological Process
GO:0006499 N-terminal protein myristoylation
GO:0018008 N-terminal peptidyl-glycine N-myristoylation
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Disease pathway
Visual phototransduction pathway
Inactivation, recovery and regulation of the phototransduction cascade pathway
The phototransduction cascade pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Membrane binding and targetting of GAG proteins pathway
Late Phase of HIV Life Cycle pathway
Synthesis And Processing Of GAG, GAGPOL Polyproteins pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
HIV Life Cycle pathway
Visual phototransduction pathway
HIV Infection pathway
The phototransduction cascade pathway
Inactivation, recovery and regulation of the phototransduction cascade pathway
Assembly Of The HIV Virion pathway
Disease pathway
The phototransduction cascade pathway
Visual phototransduction pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
Disease pathway
Inactivation, recovery and regulation of the phototransduction cascade pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A2AJH3
UniProt Splice Variant
Entrez Gene 18108
UniGene Mm.392918 Mm.432152 Mm.472809 Mm.65021
RefSeq NM_001290370 XM_006497392 NM_001290368 NM_001290369 NM_008708 XM_006497393
OMIM
CCDS CCDS70971 CCDS15644 CCDS70972
HPRD
IMGT
MGI ID MGI:1202298
MGI Symbol Nmt2
EMBL AL732620 AL928883
GenPept
RNA Seq Atlas 18108