Version 5.4
Mus musculus Protein: Ltbp3
Summary
InnateDB Protein IDBP-133061.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ltbp3
Protein Name latent transforming growth factor beta binding protein 3
Synonyms Ltbp2; mFLJ00070;
Species Mus musculus
Ensembl Protein ENSMUSP00000080214
InnateDB Gene IDBG-133057 (Ltbp3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0050431 transforming growth factor beta binding
Biological Process
GO:0001501 skeletal system development
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0030502 negative regulation of bone mineralization
GO:0032331 negative regulation of chondrocyte differentiation
GO:0036363 transforming growth factor beta activation
GO:0045780 positive regulation of bone resorption
GO:0046849 bone remodeling
GO:0060349 bone morphogenesis
GO:0060430 lung saccule development
GO:1902462 positive regulation of mesenchymal stem cell proliferation
GO:2000741 positive regulation of mesenchymal stem cell differentiation
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0031012 extracellular matrix
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1101355
InterPro IPR000742 Epidermal growth factor-like domain
IPR001881 EGF-like calcium-binding domain
IPR017878 TB domain
PFAM PF00008
PF07645
PF00683
PRINTS
PIRSF
SMART SM00181
SM00179
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9CVK2
UniProt Splice Variant
Entrez Gene 16998
UniGene
RefSeq NP_032546
MGI ID
MGI Symbol Ltbp3
OMIM
CCDS CCDS37891
HPRD
IMGT
EMBL AC134563 AK007774
GenPept BAB25247

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca