InnateDB Protein
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IDBP-133317.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Cbll1
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Protein Name
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Casitas B-lineage lymphoma-like 1
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Synonyms
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AI467391; c-Cbl-like; Hakai;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000099038
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InnateDB Gene
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IDBG-133313 (Cbll1)
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Protein Structure
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Function |
Promotes ubiquitination of several tyrosine- phosphorylated Src substrates, including CDH1, CTTN and DOK1. Targets CDH1 for endocytosis and degradation. {ECO:0000269PubMed:11836526, ECO:0000269PubMed:22252131}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
Detected in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis. {ECO:0000269PubMed:11836526}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated |
Total |
15
[view]
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Protein-Protein |
15
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
10 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2144842
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InterPro |
IPR001841
Zinc finger, RING-type
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PFAM |
PF13639
PF14634
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PRINTS |
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PIRSF |
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SMART |
SM00184
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TIGRFAMs |
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Modification |
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SwissProt |
Q9JIY2
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PhosphoSite |
PhosphoSite-Q9JIY2
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
104836
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UniGene |
Mm.490990
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RefSeq |
NP_598809
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MGI ID |
3VK6
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MGI Symbol |
Cbll1
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OMIM |
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CCDS |
CCDS56834
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HPRD |
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IMGT |
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EMBL |
AF167441
AK049141
AK166017
BC019529
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GenPept |
AAF89617
AAH19529
BAC33568
BAE38522
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