Mus musculus Protein: Gpx5
Summary
InnateDB Protein IDBP-133386.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gpx5
Protein Name glutathione peroxidase 5
Synonyms Arep; AV379049;
Species Mus musculus
Ensembl Protein ENSMUSP00000004456
InnateDB Gene IDBG-133384 (Gpx5)
Protein Structure
UniProt Annotation
Function Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Epididymis.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004602 glutathione peroxidase activity
Biological Process
GO:0006979 response to oxidative stress
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:104886
InterPro IPR000889 Glutathione peroxidase
IPR012336 Thioredoxin-like fold
PFAM PF00255
PF13098
PF13192
PF13462
PF13905
PRINTS PR01011
PIRSF PIRSF000303
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P21765
PhosphoSite PhosphoSite-
TrEMBL Q8CC60
UniProt Splice Variant
Entrez Gene 14780
UniGene Mm.1332
RefSeq NP_034473
MGI ID
MGI Symbol Gpx5
OMIM
CCDS CCDS26270
HPRD
IMGT
EMBL AC124460 AK033841 M68896 X53780
GenPept AAA37729 BAC28492 CAA37796