Version 5.4
| Mus musculus Protein: Serac1 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-133435.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Serac1 | ||||||||
| Protein Name | serine active site containing 1 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000024570 | ||||||||
| InnateDB Gene | IDBG-133431 (Serac1) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Plays an important role in the phosphatidylglycerol remodeling that is essential for both mitochondrial function and intracellular cholesterol trafficking. May catalyze the remodeling of phosphatidylglycerol and be involved in the transacylation- acylation reaction to produce phosphatidylglycerol-36:1. May be involved in bis(monoacylglycerol)phosphate biosynthetic pathway (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Endoplasmic reticulum {ECO:0000250}. Mitochondrion {ECO:0000250}. Note=Localizes at the endoplasmic reticulum and at the endoplasmic reticulum-mitochondria interface. {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Testis. {ECO:0000269PubMed:15722415}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:2447813 | ||||||||
| InterPro |
IPR012908
GPI inositol-deacylase PGAP1-like IPR016024 Armadillo-type fold IPR027417 P-loop containing nucleoside triphosphate hydrolase IPR029058 Alpha/Beta hydrolase fold |
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| PFAM |
PF07819
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q3U213 | ||||||||
| PhosphoSite | PhosphoSite-BAB31833 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 321007 | ||||||||
| UniGene | Mm.5548 | ||||||||
| RefSeq | NP_796285 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Serac1 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS28366 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK019677 AK154605 AK155571 AK162246 AK170498 BC119594 BC119595 | ||||||||
| GenPept | AAI19595 AAI19596 BAB31833 BAE32707 BAE33329 BAE36813 BAE41837 | ||||||||