InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Utrn

Summary

InnateDB Protein

IDBP-133667.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Utrn

Protein Name

utrophin

Synonyms

AA589569; Dmdl; DRP;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000076093

InnateDB Gene

IDBG-133665 (Utrn)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	31 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005178	integrin binding
GO:0005488	binding
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0017166	vinculin binding
GO:0019901	protein kinase binding

Biological Process

GO:0001954	positive regulation of cell-matrix adhesion
GO:0007527	adult somatic muscle development
GO:0016192	vesicle-mediated transport

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0016010	dystrophin-associated glycoprotein complex
GO:0016020	membrane
GO:0030175	filopodium
GO:0031527	filopodium membrane
GO:0031594	neuromuscular junction
GO:0043234	protein complex
GO:0045202	synapse
GO:0070062	extracellular vesicular exosome
GO:0070938	contractile ring

Protein Structure and Domains

PDB ID

MGI:104631

InterPro

IPR000433 Zinc finger, ZZ-type
IPR001202 WW domain
IPR001715 Calponin homology domain
IPR002017 Spectrin repeat
IPR010989 t-SNARE
IPR015153 EF-hand domain, type 1
IPR015154 EF-hand domain, type 2
IPR016024 Armadillo-type fold
IPR016344 Dystrophin/utrophin
IPR018159 Spectrin/alpha-actinin

PFAM

PF00569
PF00397
PF00307
PF00435
PF09068
PF09069

PRINTS

PIRSF

PIRSF002341

SMART

SM00291
SM00456
SM00033
SM00150

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt