Mus musculus Protein: Gabrr1 | |||||||||||||||
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Summary | |||||||||||||||
InnateDB Protein | IDBP-134410.6 | ||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
Gene Symbol | Gabrr1 | ||||||||||||||
Protein Name | gamma-aminobutyric acid (GABA) C receptor, subunit rho 1 | ||||||||||||||
Synonyms | GABA-C; | ||||||||||||||
Species | Mus musculus | ||||||||||||||
Ensembl Protein | ENSMUSP00000029947 | ||||||||||||||
InnateDB Gene | IDBG-134408 (Gabrr1) | ||||||||||||||
Protein Structure | |||||||||||||||
UniProt Annotation | |||||||||||||||
Function | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission (By similarity). {ECO:0000250}. | ||||||||||||||
Subcellular Localization | Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. | ||||||||||||||
Disease Associations | |||||||||||||||
Tissue Specificity | |||||||||||||||
Comments | |||||||||||||||
Interactions | |||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||||||
PDB ID | MGI:95625 | ||||||||||||||
InterPro |
IPR006028
Gamma-aminobutyric acid A receptor/Glycine receptor alpha IPR006029 Neurotransmitter-gated ion-channel transmembrane domain IPR006201 Neurotransmitter-gated ion-channel IPR006202 Neurotransmitter-gated ion-channel ligand-binding IPR008057 Gamma-aminobutyric-acid A receptor, Rho IPR008058 Gamma-aminobutyric-acid A receptor, Rho1 |
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PFAM |
PF02932
PF02931 |
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PRINTS |
PR00253
PR00252 PR01670 PR01671 |
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PIRSF | |||||||||||||||
SMART | |||||||||||||||
TIGRFAMs | |||||||||||||||
Post-translational Modifications | |||||||||||||||
Modification | |||||||||||||||
Cross-References | |||||||||||||||
SwissProt | P56475 | ||||||||||||||
PhosphoSite | PhosphoSite-P56475 | ||||||||||||||
TrEMBL | S4R1B1 | ||||||||||||||
UniProt Splice Variant | |||||||||||||||
Entrez Gene | 14408 | ||||||||||||||
UniGene | Mm.14116 | ||||||||||||||
RefSeq | NP_032101 | ||||||||||||||
MGI ID | |||||||||||||||
MGI Symbol | Gabrr1 | ||||||||||||||
OMIM | |||||||||||||||
CCDS | CCDS18021 | ||||||||||||||
HPRD | |||||||||||||||
IMGT | |||||||||||||||
EMBL | AF024620 AL670464 CH466538 | ||||||||||||||
GenPept | AAB81964 CAM45896 EDL05489 | ||||||||||||||