InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Gabrr1

Summary

InnateDB Gene

IDBG-134408.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gabrr1

Gene Name

gamma-aminobutyric acid (GABA) C receptor, subunit rho 1

Synonyms

GABA-C

Species

Mus musculus

Ensembl Gene

ENSMUSG00000028280

Encoded Proteins

IDBP-134410

gamma-aminobutyric acid (GABA) C receptor, subunit rho 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000146276:
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 4:33132521-33163588

Strand

Forward strand

Band

Transcripts

ENSMUST00000029947

ENSMUSP00000029947

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004890	GABA-A receptor activity
GO:0005230	extracellular ligand-gated ion channel activity
GO:0005254	chloride channel activity

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0007165	signal transduction
GO:0034220	ion transmembrane transport
GO:1902476	chloride transmembrane transport

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0034707	chloride channel complex
GO:0045202	synapse
GO:0045211	postsynaptic membrane