InnateDB Protein
|
IDBP-134472.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Nudt5
|
Protein Name
|
nudix (nucleoside diphosphate linked moiety X)-type motif 5
|
Synonyms
|
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000026927
|
InnateDB Gene
|
IDBG-134470 (Nudt5)
|
Protein Structure
|
|
Function |
Hydrolyzes with similar activities ADP-ribose and ADP- mannose. Can also hydrolyzes ADP-glucose (40% of ADP-ribose activity) and other nucleotide sugars with low activity (10%). Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA.
|
Subcellular Localization |
|
Disease Associations |
|
Tissue Specificity |
Widely expressed. Most abundant in liver.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
16 [view]
|
|
|
Molecular Function |
|
Biological Process |
GO:0006139
|
nucleobase-containing compound metabolic process
|
GO:0009191
|
ribonucleoside diphosphate catabolic process
|
|
Cellular Component |
|
PDB ID |
MGI:1858232
|
InterPro |
IPR000086
NUDIX hydrolase domain
IPR015797
NUDIX hydrolase domain-like
IPR020476
NUDIX hydrolase
|
PFAM |
PF00293
|
PRINTS |
PR00502
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q9JKX6
|
PhosphoSite |
PhosphoSite-Q9JKX6
|
TrEMBL |
A2ATT5
|
UniProt Splice Variant |
|
Entrez Gene |
53893
|
UniGene |
Mm.432123
|
RefSeq |
NP_058614
|
MGI ID |
|
MGI Symbol |
Nudt5
|
OMIM |
|
CCDS |
CCDS15667
|
HPRD |
|
IMGT |
|
EMBL |
AF222786
AK088222
AL928924
BC004571
BC049595
|
GenPept |
AAF44630
AAH04571
AAH49595
BAC40220
CAM20348
|
|
|