InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fgfr1op

Summary

InnateDB Protein

IDBP-135355.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fgfr1op

Protein Name

Fgfr1 oncogene partner

Synonyms

4930553O10Rik; FOP;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000024636

InnateDB Gene

IDBG-135351 (Fgfr1op)

Protein Structure

UniProt Annotation

Function

Required for anchoring microtubules to the centrosomes. {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Associated with gamma-tubulin. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0019901	protein kinase binding
GO:0030292	protein tyrosine kinase inhibitor activity
GO:0042803	protein homodimerization activity

Biological Process

GO:0006469	negative regulation of protein kinase activity
GO:0008284	positive regulation of cell proliferation
GO:0030307	positive regulation of cell growth
GO:0030335	positive regulation of cell migration
GO:0034453	microtubule anchoring
GO:0061099	negative regulation of protein tyrosine kinase activity