InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pde10a

Summary

InnateDB Protein

IDBP-135822.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Pde10a

Protein Name

phosphodiesterase 10A

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000024647

InnateDB Gene

IDBG-135818 (Pde10a)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
GO:0005515	protein binding
GO:0046872	metal ion binding

Biological Process

GO:0007165	signal transduction
GO:0008152	metabolic process
GO:0010738	regulation of protein kinase A signaling
GO:0043949	regulation of cAMP-mediated signaling

Cellular Component

Protein Structure and Domains

PDB ID

MGI:1345143

InterPro

IPR002073 3\'5\'-cyclic nucleotide phosphodiesterase, catalytic domain
IPR003018 GAF domain
IPR003607 HD/PDEase domain
IPR023088 3\'5\'-cyclic nucleotide phosphodiesterase
IPR029016 GAF domain-like

PFAM

PF00233
PF01590
PF13185
PF13492

PRINTS

PR00387

PIRSF

SMART

SM00065
SM00471

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F8WHK3

UniProt Splice Variant

Entrez Gene

23984

UniGene

Mm.87161

RefSeq

MGI ID

MGI Symbol

Pde10a

OMIM

CCDS

HPRD

IMGT

EMBL

AC105299 AC105300 AC122893 AC154579

GenPept