Version 5.4
Mus musculus Protein: Pclo
Summary
InnateDB Protein IDBP-135875.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pclo
Protein Name piccolo (presynaptic cytomatrix protein)
Synonyms Acz; Pico;
Species Mus musculus
Ensembl Protein ENSMUSP00000030691
InnateDB Gene IDBG-135873 (Pclo)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005522 profilin binding
GO:0005544 calcium-dependent phospholipid binding
GO:0046872 metal ion binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0016080 synaptic vesicle targeting
GO:0017157 regulation of exocytosis
GO:0019933 cAMP-mediated signaling
GO:0030073 insulin secretion
Cellular Component
GO:0030054 cell junction
GO:0045202 synapse
Protein Structure and Domains
PDB ID MGI:1349390
InterPro IPR000008 C2 domain
IPR001478 PDZ domain
IPR008899 Zinc finger, piccolo-type
IPR011011 Zinc finger, FYVE/PHD-type
PFAM PF00168
PF00595
PF13180
PF05715
PRINTS PR00360
PIRSF
SMART SM00239
SM00228
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9QYX7
PhosphoSite PhosphoSite-Q9QYX7
TrEMBL
UniProt Splice Variant
Entrez Gene 26875
UniGene Mm.471072
RefSeq NP_036125
MGI ID
MGI Symbol Pclo
OMIM
CCDS CCDS51415
HPRD
IMGT
EMBL AB083477 AB083478 AC125043 AC125533 AC144480 AC144625 AF181269 Y19185 Y19186
GenPept AAD55786 BAC53723 BAC53724 CAB60731 CAB60732

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca